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An informed patient community is forming, and regulatory agencies are reviewing claims and safety data

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The company has already flagged a US$65 million revenue headwind in Q1 2026 tied to tighter rules around compounded semaglutide shipping, and the Novo Nordisk patent case plus FDA and SEC scrutiny add another layer of uncertainty around how much of this revenue is sustainable and at what margin

However, hormones do not appear to be the only factor triggering this type of angioedema, and a few series report cases of symptomatic male subjects